The president has already addressed disparity in sentencing between powdered and crack cocaine, and will bring further attention to the drug war during his second term.
According to GQ:
According to ongoing discussions with Obama aides and associates, if the president wins a second term, he plans to tackle another American war that has so far been successful only in perpetuating more misery: the four decades of The Drug War.
Don’t expect miracles. There is very little the president can do by himself. And pot-smokers shouldn’t expect the president to come out in favor of legalizing marijuana. But from his days as a state senator in Illinois, Obama has considered the Drug War to be a failure, a conflict that has exacerbated the problem of drug abuse, devastated entire communities, changed policing practices for the worse, and has led to a generation of young children, disproportionately black and minority, to grow up in dislocated homes, or in none at all.