Students were urged to remain in their dorm rooms at Coastal Carolina University in Conway, but the gunman was believed to have fled the scene, school officials said.
The shooting occurred just before 7:30 p.m. at University Place, an apartment-style residence hall that is home to nearly 2,000 students.
“The suspect fled in a vehicle. The campus is still on lockdown, although people in classrooms were allowed to go home. Those in dorms were advised to stay inside,” said Mona Prufer, a university spokeswoman.